›› 2012, Vol. 24 ›› Issue (5): 376-378.doi: 10.3969/j.issn.1004-616x.2012.05.014

• 肿瘤防治 • Previous Articles     Next Articles

Expression characteristics of serum AFP, CEA and CA19-9 in patients with gastrointestinal malignant tumors

HUANG Su-ying;HUANG Chang-ming;TIAN Jun;CHEN Hua   

  1. (1. Public Health Academy, Fujian Medical University, Fuzhou 350004; 2. Peace Office, Xiamen Entry-Exit Inspection and Quarantine Bureau, Xiamen 361000; 3. Surgical Oncology, Fujian Medical University Affiliated Union Hospital, Fuzhou 350001, Fujian, China)
  • Received:2012-05-15 Revised:2012-07-19 Online:2012-09-30 Published:2012-09-30
  • Contact: CHEN Hua

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Abstract: OBJECTIVE: To explore expression characteristics of serum tumor markers AFP，CEA， CA19-9 in patients with the gastrointestinal malignant tumors. METHODS：Expression levels of AFP，CEA，CA19-9 in serum of 126 patients with gastrointestinal cancers were analyzed by Roche automatic electrochemical luminescence， and the relationship of these markers with clinicopathological factors were studied. RESULTS：Serum CEA expression increased with the depth of tumor invasion，clinical stage，and distant metastasis，the difference was statistically significant (P<0.05). Serum CA19-9 expression levels increased significantly with clinical stage，and distant metastasis difference (P<0.05). Serum level of AFP expression was not significantly different between the various clinical pathological factors. CONCLUSION： Expression levels of serum CEA，CA19-9 were closely related to the clinical condition of patients with gastrointestinal cancers.

Key words: AFP, CEA, CA19-9, gastrointestinal tumors, tumor markers